Gastrointestinal stromal tumor | Tumor

CURE’s gastrointestinal stromal tumor page features the latest cancer news and updates on gastrointestinal stromal tumors Through articles, videos, podcasts, and more, CURE brings readers the insights of experts, cancer survivors, patients, and advocates to ensure everyone is up to date in the gastrointestinal stromal tumor.

Endoscopic Procedure Removes GIST Without Surgery

May 1st 2025, 7:00pm

Article

A new endoscopic tunneling method, STER, allowed a patient to have a GIST removed without surgery, allowing quicker recovery and fewer complications.

First Patient Dosed in Trial of Ziftomenib for Advanced GIST

May 1st 2025, 3:03pm

Article

A phase 1 trial has initiated and is investigating treatment with ziftomenib plus Gleevec in advanced GIST following progression on Gleevec.

SIRT With 90Y Resin Microspheres Provides Benefit in GIST Liver Metastases

April 29th 2025, 1:00pm

Article

SIRT with 90Y resin microspheres led to durable disease control in patients with gastrointestinal stromal tumor liver metastases resistant to TKI therapy.

Alternating Glivec and Stivarga Doesn't Improve Advanced GIST Outcomes

April 28th 2025, 9:00pm

Article

Alternating between Glivec and Stivarga therapy didn't impact survival outcomes; it led to more toxicity and discontinuations in patients with GIST.

Treatment With HT-KIT Shows Early Preclinical Activity in GIST Models

April 27th 2025, 6:00pm

Article

HT-KIT, a novel targeted therapy for GIST, demonstrated the ability to reduce tumor burden in humanized mouse models and induce tumor cell death.

RECKGIST Score May Predict Recurrence in Neurofibromatosis Type 1 GISTs

March 12th 2025, 1:00pm

Article

RECKGIST score may predict recurrence in neurofibromatosis type 1 GISTs, potentially guiding treatment decisions, according to study findings.

Pimitespib Associated With Stable Disease for Some Patients With GIST

March 11th 2025, 1:00pm

Article

Treatment with pimitespib was associated with stable disease in two-thirds of patients with advanced gastrointestinal stromal tumors.

Gleevec Response in GIST May Be Linked to Mutational Profile

March 10th 2025, 1:00pm

Article

Gleevec response in GIST varies by mutational profile, with KIT-exon-11 mutation linked to better outcomes, emphasizing mutation testing for treatment decisions.

GI Bleeding Significantly Impacts GIST Treatment Outcomes

February 12th 2025, 8:00pm

Article

The prognosis of patients with gastrointestinal stromal tumors is significantly impacted by gastrointestinal bleeding.

Neoadjuvant TKI Prior to Surgery Has Surgical Benefit in Non-Metastatic GIST

February 7th 2025, 2:00pm

Article

Patients with non-metastatic GIST treated with neoadjuvant TKIs prior to surgery experienced a benefit which led to less invasive or complex surgeries.