This September, MJH Life Sciences, the parent company of 

, celebrates our 25th anniversary. The innovation in health care over the past 25 years has been nothing short of miraculous! Together, we have witnessed significant advances that have provided new cancer treatments. Throughout these changes and into the future, MJH Life Sciences is committed to providing high-quality information and education.

Cancer-related fatigue is a common side effect most survivors experience after receiving treatment. This kind of fatigue is felt physically, mentally and emotionally, which can significantly affect one’s quality of life. It creates a challenge for all aspects of everyday life, including work, relationships with loved ones and even the completion of daily tasks, such as laundry. Focusing energy on cancer-related fatigue is crucial, and this fall issue of Heal dives into how survivors can help manage that side effect.

“Cancer-related fatigue is a fatigue that is pervasive throughout the body,” says Luke Peppone, of the University of Rochester in New York. “It’s not due to a lack of rest — additional rest does not alleviate this fatigue. When people have pervasive fatigue, it could be mental fatigue or physical.”

We hear two survivors’ stories about how they’ve learned to 

by taking breaks and making the most of energy spurts. Elsewhere in this feature, we speak with a director of cancer rehabilitation who emphasizes the importance of exercising, especially when the fatigue is intense, and the steps to take to start noticing an improvement.

Also in this issue, the side effect of hearing loss from chemotherapy is explored. We speak with a distinguished professor from the University of South Florida about what survivors can do to maintain their hearing and what to avoid.

, a comedian and metastatic breast cancer survivor, discusses her nine-year experience with the disease and how she cultivates a community on social media. Sharing short-form videos on Instagram and TikTok has given her a chance to share the good, the bad and the ugly, which can be “the most healing part.”

 to spice up your cookbook. These dishes are packed with essential vitamins and minerals, providing you with the sustenance your body needs. If you’d like to cozy up on a rainy day, I encourage trying the turmeric ginger latte.

As always, we hope you find our stories inspirational and informative. Thank you for reading.

For more news on cancer updates, research and education, don’t forget to 

Articles

MJH Life Sciences celebrates its 25th anniversary, highlighting significant healthcare advancements, particularly in cancer treatment. The issue addresses cancer-related fatigue, a common post-treatment side effect affecting survivors' quality of life. Experts and survivors share strategies for managing this fatigue, emphasizing exercise and energy management. The issue also explores chemotherapy-induced hearing loss and offers advice on maintaining hearing health. A survivor spotlight features Annie Bond, a comedian with metastatic breast cancer, who uses social media to share her journey. Additionally, new fall recipes are provided to support nutritional needs.

Cancer-related fatigue is felt physically, mentally and emotionally, which can significantly affect one’s quality of life. 

Powering Through Fatigue After Cancer

Sweet Potato Fries With Garlic Yogurt Dip 

1 to 2 tablespoons extra virgin olive oil, depending on desired consistency of dip

1 to 2 tablespoons water, depending on desired consistency of dip

2 to 3 tablespoons fresh herbs for extra flavor, e.g., parsley and dill

2. Make the fries: Cut sweet potatoes into evenly sized matchsticks, about 1/4-inch wide. Soak fries in cold water for at least 30 minutes. Rinse, drain and pat dry.

3. Transfer fries to a dry bowl or zip-close bag, add oil and toss to evenly coat the fries.

4. Add seasonings to bowl or zip-close bag and toss to evenly coat the fries.

5. Transfer fries to a parchment-covered baking sheet and spread out in an even layer.

6. Bake for 40 minutes or until crispy. Be sure to flip the fries halfway through baking.

7. While the fries are in the oven, prepare the garlic yogurt dip. Place all dip ingredients in a small bowl and mix until well combined.

8. Remove the baking sheet from the oven. Let fries cool, season with salt and pepper to taste, then rest for 3 to 5 more minutes.

1 ½ cups unsweetened almond, soy or coconut milk

1 tablespoon minced fresh ginger or ¼ teaspoon ground ginger

½ teaspoon ground cinnamon, plus more for serving

½ teaspoon coconut sugar or ½ teaspoon maple syrup

1. Whisk all ingredients together in saucepan and bring to a simmer over medium heat. Be careful not to let it burn. 

2. Strain ginger solids (or leave them, if desired). 

3. Whisk or froth before serving and sprinkle with additional cinnamon. 

8-ounce package tempeh, finely chopped (I prefer Lightlife Original Flavor) 

1 cup canned coconut milk (use unsweetened almond milk for lower fat and calories)

 1. Combine all ingredients for the tempeh with marinade in a bowl. Stir well. Refrigerate for at least 1 hour or up to overnight. 

2. When the marinade is ready, add oil and heat a large skillet on medium-high. Saute garlic, ginger and onion for 5 minutes. Add spices and cook for 1 minute. Add kale and saute for another minute or two. 

3. Add tomato sauce, coconut milk and tempeh with marinade. Add Sriracha if you want it really spicy. 

4. Simmer on medium-low heat for 15 minutes until cooked through and the sauce thickens. 

5. Steam or stir-fry the riced cauliflower until tender. 

6. Serve over riced cauliflower and top with chopped cilantro.

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This text provides three distinct recipes: Sweet Potato Fries with Garlic Yogurt Dip, Turmeric Ginger Latte, and Tempeh Tikka Masala. Each recipe includes a list of ingredients and step-by-step instructions for preparation. The Sweet Potato Fries are baked and served with a garlic yogurt dip, while the Turmeric Ginger Latte is a spiced, frothy beverage. The Tempeh Tikka Masala features marinated tempeh in a rich, spiced sauce, served over riced cauliflower. These recipes offer a variety of flavors and dietary options for diverse culinary preferences.

Heal at Home

Try out these 3 recipes to add different flavor combinations to your meals and provide adequate nutrition for cancer survivors.

Comforting Fall Recipes With Some Spice for Cancer Survivors

With technology advancements from the past 10 years, cancer communities are now more accessible via the internet. However, in 2015, Annie Bond, a comedian and survivor of metastatic breast cancer longed for a community of people she could empathize with.

After Bond, then 26, noticed a lump in her breast and some weight gain in her left armpit, she visited her gynecologist and two other doctors. Nevertheless, each of them told her she was “too young for cancer,” Bond recalled during an interview with 

. Nine months passed before anyone recommended that she undergo an ultrasound and other diagnostic testing, but by then, her cancer had metastasized to her liver, she said.

When Bond finally received her diagnosis of metastatic breast cancer, her first oncologist said she would have three to five years to live.

“Next year, it’ll be 10 years, so he was incorrect,” Bond said. “It took me about two years to reach no evidence of disease, but since, I have basically stayed there, which has been amazing.”

Bond underwent multiple surgeries, including a procedure to remove the tumors in her liver, a lumpectomy to remove the breast tumors and a procedure to remove her ovaries after freezing her eggs. Her treatment also consisted of eight weeks of radiation, and she started taking Ibrance (palbociclib) pills, which has “been the most successful line of treatment I’ve had,” she said.

Focusing Energy on Cancer-Related Fatigue

Bond felt alone because she didn’t know anyone else who had experienced metastatic breast cancer, especially at her age. So, when social media platforms, such as Instagram and TikTok, began opening the door to different communities, Bond shared her story.

“One of the biggest things that I have struggled with was feeling all that guilt [alone],” Bond said. “The unfortunate thing about being in the metastatic community is [that] you do lose a lot of people because it is a cruel and unfair disease. I think in those first couple of losses, I just started to feel really angry and helpless. Then I realized it doesn't matter who's talking — if one of us is succeeding, we’re all succeeding.”

In a place like social media, breaking down the barriers of perfection has been important — particularly in discussing the good, the bad and the ugly.

“To [patients and survivors], because [cancer] is a dark and sad and awful disease, I think that’s why it’s so great that we have social media where people can find so many inside jokes and all of that fun stuff together,” Bond explained. “But I think the most healing part of this community is when we feel those dark thoughts that only we have, because we all share those thoughts.”

Others with cancer — including adolescents and young adults (AYAs) with cancer — have thanked Bond for speaking at hospitals about her good and bad experiences with cancer.

“The first time I was brave enough to speak up about [those dark thoughts], at a hospital, I can’t tell you — every single person who came up to me after was like, ‘Thank you so much for talking about that because I’ve been through that.’ And I thought I wasn’t allowed to tell anybody because I had already put so much on them,” Bond said. “We don’t ask to get cancer. We know that cancer can happen to anybody at any time. You can’t be too young for cancer.”

Because topics related to cancer can be difficult to discuss, Bond combines her passion for cancer advocacy and comedy to create content on social media.

“I try to find a balance between just sharing my life and then also presenting very important information in a digestible way,” she explained. “One of the hardest things about being an AYA, especially somebody like me who got a degree in acting [and] didn’t get a science degree, [is that] I have to try so hard to be good at it.”

She ensures that her facts are accurate by doing research and talking with her doctor before sharing what she has learned with her social media followers.

“Another thing I love is just showing people that you can have a fun and full and beautiful life, even with the worst,” Bond said. “I think that it's so helpful for people [and] for me. The reason I wanted to be a sitcom star when I was young is because no matter what is going on [in your life, if] you can sit and you can just laugh for a minute, it's really helpful.

“I would say laughter is the best medicine besides the actual medicine.”

Annie Bond, a comedian and metastatic breast cancer survivor, shares her journey of diagnosis, treatment, and advocacy. Initially dismissed by doctors due to her age, her cancer metastasized before diagnosis. Despite a grim prognosis, Bond achieved no evidence of disease and found solace in online cancer communities. She uses social media to connect with others, combining humor and advocacy to discuss the realities of cancer. Bond emphasizes the importance of community support and open discussions about cancer's challenges, highlighting the therapeutic power of laughter alongside medical treatment.

Annie Bond, a comedian and survivor of metastatic breast cancer, started making videos on social media to cultivate a community she needed after her diagnosis.

A Metastatic Breast Cancer Survivor Finds Comfort in Social Media

As a college student and windsurfer on the Olympic development team, the sudden abnormal exhaustion Michael Cramer experienced revealed that something was very wrong. At age 19 in July 2020, Cramer and his mom, Ashlee, decided it was necessary for him to visit the hospital, despite the ongoing COVID-19 pandemic.

The next month, he received a diagnosis of hepatosplenic T-cell lymphoma. This subtype of lymphoma (a blood cancer) is considered rare, aggressive and is more common in adolescents and young adults, according to a study published in Blood.

Cramer received three rounds of chemotherapy, radiation and a bone marrow transplant from a donor in October. However, in January 2021, he developed graft-versus-host-disease (GVHD),

which occurs when the donated stem cells (graft) identify the patients’ cells (host) as a threat and attacks the host’s tissue, as defined by the Cleveland Clinic.

Four years later, Cramer, now 23, is in remission and receives immunosuppressants to help treat his GVHD. Still, he experiences cancer-related fatigue, which he says is likely from a mix of his cancer treatment and GVHD.

“Now I still deal with chronic fatigue as one of my main [side effects],” says Cramer, of Miami. “I get energy in spurts and bouts, but I always have to rest whenever we go somewhere to speak at a [cancer advocacy] event.”

His quality of life, he says, has been heavily affected by cancer-related fatigue. At times, he’ll wake up feeling motivated to have a productive day but realizes he’s only able to accomplish a few tasks because of intense fatigue. Completing smaller tasks now makes him feel more exhausted than they used to, he explains. After exercising for an hour, Cramer finds himself having to rest for a while once completing his repetitions.

“I just need to rest a lot more than I used to and need to take more time to sit down,” he says. “I don’t like sitting down a lot. I like to be very active, so it’s been hard for me to accept this. I try to push through, but then I end up very exhausted. It’s an interesting balance: figuring out whether I’m doing enough or doing too much.”

To add to the challenge, Cramer notes that his energy spurts come at random times during the day, which he tries to take advantage of. When these energy spurts align with his availability, he tries to use that time to work out and if it’s during the evening hours, he takes walks on the beach with his mom.

Ashlee — who left her career to become his caregiver full time — helps when he feels overly fatigued. She also advocates for him to rest when necessary because “she knows me and my fatigue so well,” Cramer says.

Now when he has those spurts of energy, he spends time with friends, challenges himself with Lego projects and creates content on social media with his mom about his cancer experience.

Cancer-related fatigue is a common side effect most survivors experience, especially because it can be caused by both the cancer and its treatment, according to guidelines from the National Comprehensive Cancer Network. This type of fatigue may last months to years after the end of treatment and “does not improve with normal amounts of rest or sleep and disrupts daily life,” the guidelines state.

“Cancer-related fatigue is a fatigue that is pervasive throughout the body. The best way to describe it is the fatigue someone feels when they have the flu,” adds Luke Peppone, associate professor in the Department of Surgery, Cancer Control and Cancer Center at the University of Rochester in New York. “It’s not due to a lack of rest — additional rest does not alleviate this fatigue. When people have pervasive fatigue, it could be mental fatigue or physical.”

The source of cancer-related fatigue can vary, Peppone says. Almost all types of cancer treatments lead to some degree of fatigue, but chemotherapy contributes the most. Survivors who received chemotherapy for their cancer have “at least a 90% chance or greater of experiencing cancer-related fatigue,” Peppone says. When treatment ends, most people’s fatigue is alleviated within six months. However, in about 30% of survivors, he emphasizes that the fatigue doesn’t go away within six months and may last one to two years following treatment.

“Now the studies are being followed up longer and longer,” he says. “We find that five years out of treatment, 30% still have fatigue and even up to 10 years out now, as we extend the studies.”

Similarly, immunotherapy (a type of cancer treatment that helps the immune system destroy cancer) may also be related to cancer-related fatigue because the immune system can react against different organs, so survivors are “going to see some level of fatigue,” Peppone explains. Even nonintravenous therapies (treatments not infused through a vein), such as radiation and surgery, may cause some fatigue, but mostly because of the recovery process following these treatments, he says.

How Interventions Can Improve Cancer-Related Fatigue

Although cancer-related fatigue can alter quality of life and the way daily tasks are

completed, there are still ways to mitigate this side effect. Several practices to help manage cancer-related fatigue were updated in the 2024 American Society of Clinical Oncology (ASCO)-Society for Integrative Oncology (SIO) guidelines, which Peppone helped review. Based on further research, some interventions for fatigue were shown not to work, while many others were confirmed to be helpful.

“One thing not recommended during a person’s cancer experience is wakefulness agents (stimulants to help with alertness) and psychostimulants. So, no drugs [of that type] are recommended at all,” Peppone says.

A significant intervention that has been shown to help with managing cancer-related fatigue is exercise or a type of physical activity.

“There’s been evidence from the American College of Sports Medicine that doing 150 minutes of physical activity per week helps,” says Dr. Erin Kelly, director of Cancer Rehabilitation at Thomas Jefferson University Hospital in Philadelphia.

“I say physical activity because a lot of people don’t find exercise as something they enjoy, but some of our daily activities are really a form of exercise.”

However, Kelly notes that it may take a 12-week period or longer before survivors with fatigue notice the results, recommending 30 minutes of aerobic exercise at least three times a week. She explains that a breathlessness scale from zero to 10 helps indicate how much physical activity a person does and overall fitness. Aerobic exercise, specifically, is a 5 or 6 on the breathlessness scale, meaning a person can likely still talk but cannot sing, she says. Kelly says examples of aerobic exercise include a brisk walk or jogging.

Incorporating everyday physical activity doesn’t stop at aerobic exercise, though. Kelly explains that adding resistance training is important, but this doesn’t always mean lifting heavy weights; the key is repetition until it’s difficult to complete the next set of exercises.

“Being physically active is the best thing you can do to both prevent fatigue from occurring in the first place or treat it once it has occurred,” says Dr. Jennifer A. Ligibel, of the Breast Oncology Center at the Dana-Farber Cancer Institute and associate professor at Harvard Medical School, both in Boston. “It’s important to start slow so that you don’t wear yourself out, especially if you’re already experiencing fatigue.”

Completing exercise while feeling cancer-related fatigue can be a large ask, so Kelly agrees it’s necessary to build up to it. Instead of starting at 30 minutes, three times a week, she suggests starting at least once a week and asking a friend to join to make it more fun while having accountability. And you don’t have to necessarily start with exercise. Opt for an enjoyable physical activity, such as gardening, yoga, tai chi or meditation.

When Diane Holland first experienced cancer-related fatigue, she had trouble determining whether she should build her stamina or rest. Now she goes on a walk and tries to push herself to do something physical daily. Like Cramer, Holland finds that her cancer-related fatigue varies each day.

Holland, 65, of Bensalem, Pennsylvania, has received four diagnoses for three cancer types since 2019. She first received a diagnosis of lung cancer in June 2019, for which she underwent surgery to remove the lower lobe of her left lung and was told she wouldn’t need further treatment. In December of that year, she was diagnosed with bladder cancer and underwent a procedure to remove the tumor. Following a routine mammogram, she received a diagnosis of breast cancer in 2021 and underwent a double mastectomy, chemotherapy, radiation and reconstructive surgery.

During the summer of 2023, she received her fourth diagnosis: a recurrence of her lung cancer. A full-time sales support employee at a multinational company, Holland says fatigue takes on a new meaning during treatment — mentally, physically and emotionally. Between appointments, working remotely and taking days off to recover from treatment, she has been able to balance her work life and fatigue. On the every other Tuesdays she receives chemotherapy, she takes the day off from work but is able to work the following two days after receiving steroids and antinausea medication. By Friday, she says the steroids wear off and she has to take another day off from work.

The level of fatigue Holland experiences from chemotherapy causes her to crash, which also affects the way she processes sound, she says.

“The fatigue just takes you out,” she explains. “It’s not just lying in bed, watching TV. I can’t really process the sounds. I just lay quietly, whether it’s in bed or on the sofa, just no sound.”

On posttreatment days when Holland’s fatigue is more manageable, she visits Kelly and a nutritionist at Jefferson hospital, where they discuss exercise and diet plans. Holland notes that trying several forms of integrative oncology, such as Reiki (a form of energy healing) and oncology massages, help her have some peace of mind. Her specialists have helped her manage fatigue, but Kelly has also helped change Holland’s mindset toward it.

“The most important thing that Dr. Kelly said to me is something that totally changed how I’m interacting with my fatigue,” Holland says. “She said, ‘You’re tired when you’re out and you’re tired when you’re home. Don’t let that stop you from going out to do the things you enjoy. Maybe just keep going out even though you feel tired and see if that brings you more energy.’

“It totally does. It was life-changing for me.”

Mitigating Cancer-Related Fatigue at Home

Energy conservation and using energy wisely are crucial, as Cramer and Holland both describe. Asking for help from loved ones is an effective way to help conserve energy, especially when there’s a task or event worth spending it on, Kelly emphasizes. Even getting help doing everyday tasks, such as laundry, may help.

“If people have cancer-related fatigue, energy conservation is something we talk about a lot,” Kelly says. “Try to conserve your energy to do the things you would like to do. Even if it’s someone else willing to help you do the laundry today because you’d rather go out and walk the dog. This can be taking that help and asking friends and family for favors for things that don’t give you joy and wouldn’t be adding to your physical fitness.”

Prioritizing how to spend each day by scheduling activities during energy spurts and delegating tasks to other people can help and is sometimes necessary, says Ligibel. Noticing trends in energy levels may also be helpful, particularly when completing tasks that require more energy, such as going grocery shopping. She notes that if a person feels more fatigued in the afternoon, then it may be best to structure their day around that.

Practicing mindfulness through cognitive behavioral therapy — another intervention listed in the ASCO-SIO guidelines — can be helpful, even online, Ligibel says.

“Seek out those opportunities for mindfulness because there’s data that it has been helpful,” she suggests. “Try to build that into your day because finding a quiet time and space for that — it’s not always so easy.”

Michael Cramer, a young athlete, was diagnosed with hepatosplenic T-cell lymphoma, a rare and aggressive cancer, at 19. Despite undergoing chemotherapy, radiation, and a bone marrow transplant, he developed graft-versus-host disease (GVHD), leading to chronic cancer-related fatigue. This fatigue, common among cancer survivors, persists despite rest and significantly impacts daily life. Effective management strategies include exercise, energy conservation, and mindfulness practices. Interventions like aerobic and resistance training, alongside cognitive behavioral therapy, can help mitigate fatigue and improve quality of life for survivors.

Feature

Fatigue is a common side effect that may linger for years following cancer treatment. Experts and survivors talk about ways to help find a balance between life and fatigue.

Heal Fall 2024

Powering Through Fatigue After Cancer

Comforting Fall Recipes With Some Spice for Cancer Survivors

A Metastatic Breast Cancer Survivor Finds Comfort in Social Media

Focusing Energy on Cancer-Related Fatigue

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