She serves as the assistant director of Education Programs at the Association of Cancer Care Centers and works as a PRN Heart Transplant nurse at MedStar Washington Hospital Center, located in Washington, DC.

Kimberly Demirhan

There is an urgent need for more inclusive and community-focused cancer clinical trials, according to Kimberly (Cary) Demirhan.

A Call to Action for More Inclusive Clinical Trials in Cancer Care

There is an urgent need for more inclusive and community-focused cancer clinical trials, according to Kimberly (Cary) Demirhan, a registered nurse, who said that traditional trials often exclude patients from underrepresented populations.

The exclusion of these patients can range from racial and ethnic minorities and older adults to rural residents. Demirhan explored this unmet need further in research published by the Association of Cancer Care Centers (ACCC) to explore strategies that broaden access.

To delve deeper into this topic, Demirhan sat down for an interview with CURE in which she discusses the importance of including real-world patients in clinical trials, including those with other health conditions, who are older, or live in rural areas.

A major goal of your work is to ensure that trials reflect real-world patients. What does that mean for patients who may have other health conditions, be older, or live in rural areas?

Our goal in the work we're doing is to ensure that trials are accessible to everyone. The importance of this is that we want to make sure the patients we are using these trial drugs on represent all different walks of life. They should be of various ethnicities and genders, and exposed to different external environmental factors, and so on. It's really important to us that while historically, trials have had a high rate of enrollment with older white males, not every disease state affects only older white males.

So, we want to ensure that when we look at who's enrolling in trials, we broaden that scope so that people of different ethnicities and genders are all enrolled. This way, when we are looking at the safety and efficacy of these trial drugs, they are applicable to everyone who is potentially going to experience this disease type or cancer, and that those drugs are safe for everyone. It's really important that we expand our access to have a wide variety of patients enrolling in trials, to reflect the patients who are actually dealing with the disease and who are actually going to be taking that medication in the real world down the line, and to make sure that it is safe for everyone.

“Bringing Cancer Research to the Community: Strategic Approaches to Representative Oncology Clinical Trial Design,” by Dr. Nicole A Colwell, et al. ACCC Community Oncology Research Institute.

Transcript has been edited for clarity and conciseness

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Kimberly Demirhan

A Call to Action for More Inclusive Clinical Trials in Cancer Care

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