SABCS

Pre-Surgical Keytruda Provides Promising Advancement in TNBC Treatment

December 20th 2021, 8:00pm

Article

Findings from a clinical trial showed that adding Keytruda to neoadjuvant chemotherapy in patients with triple-negative breast cancer significantly improved outcomes and was overall safe and tolerable for patients.

Some Treatment Outcomes Do Not Differ Between Black and White Patients With Breast Cancer, But Disparities Persist

December 12th 2021, 8:00pm

Article

Study results showed that pathologic complete response rates were not significantly different between Black and White patients with high-risk breast cancer, but disparities still exist for other treatment outcomes.

Lynparza After Chemo May Not Greatly Impact Quality of Life in High-Risk Early Breast Cancer Subset

December 11th 2021, 3:00pm

Article

Although patients treated with Lynparza after chemotherapy may experience side effects such as fatigue and nausea/vomiting, these symptoms resolved after treatment was completed in patients with high-risk early breast cancer.

Triplet Regimen Extends Time Before Brain, Spinal Cord Metastases Worsen in Patients With Breast Cancer

December 10th 2021, 10:00pm

Article

A three-drug regimen was shown to lengthen the amount of time before cancer progressed to the central nervous system — known as central nervous system progression-free survival — in certain patients with breast cancer.

Experimental Drug Plus Chemo Boosts Survival in HER2-Positive Metastatic Breast Cancer

December 10th 2021, 5:00pm

Article

The use of pyrotinib — an experimental drug — plus the chemotherapy capecitabine extended survival compared with Tykerb and capecitabine among patients with pretreated HER2-positive metastatic breast cancer.

Novel Drug Elicits Favorable Outcomes in Advanced, Metastatic TNBC

December 10th 2021, 2:00pm

Article

Early-phase study results showed that treatment with a novel drug elicits promising outcomes in patients with advanced or metastatic triple-negative breast cancer.

Immunotherapy Before Surgery May ‘Increase the Chances’ Patients Are Cured of TNBC

December 9th 2021, 10:00pm

Video

Clinical trial results show that adding Keytruda to chemotherapy prior to surgery for triple-negative breast cancer can improve outcomes and hopefully “increase the chances for patients to be cured,” according to an expert.

Black Patients More Likely to Experience Treatment Changes That May Worsen Breast Cancer Outcomes

December 9th 2021, 8:00pm

Article

Treatment modifications in the pre-surgery setting led to a lower rate of pathologic complete response in Black patients with breast cancer, the researchers found.

Study Confirms Adding Ibrance to Endocrine Therapy May Not Improve Outcomes in Early Breast Cancer

December 8th 2021, 10:00pm

Article

The addition of Ibrance to endocrine therapy was not associated with preventing disease recurrence in patients with hormone receptor (HR)–positive, human epidermal growth factor receptor 2 (HER2)–negative early breast cancer, according to final results of the phase 3 PALLAS trial.

Medication Used to Treat Diabetes Fails to Improve Breast Cancer Outcomes

December 8th 2021, 4:00pm

Article

Researchers hypothesized that metformin — a medication that helps lower insulin levels in patients with diabetes and is associated with inducing weight loss — might improve breast cancer outcomes.